Metformin For Weight Loss in Non-Diabetics (2024)

Metformin is the most common medicine prescribed for diabetics by physicians. If you are suffering from type 2 diabetes, along with obesity, metformin helps to a great extent. It manages blood sugar levels for patients suffering from Diabetes 2.

Metformin helps you manage diabetes by controlling your weight. So, is it possible that non-diabetics in weight watchers can use metformin for weight loss? It is worth noticing that metformin is not recommended by the FDA as a weight loss pill.

However, there are a few scenarios where Metformin comes in handy. Since there is no treatment for diabetes, Metformin is administered at various dosages as appropriate, throughout life along with diet and lifestyle practices.

Is Metformin Effective For Weight Loss?

Metformin works with other prescription medicines to treat diabetes which reduces insulin levels in the bloodstream. As metformin prompts one to eat less, the reduction in appetite is one of the probable reasons for weight loss. It also affects the way your body stores or uses fat.

Metformin For Weight Loss in Non-Diabetics
Date of Birth:1922
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Height:the greater increase in height 
Weight:Metformin is an effective drug to reduce weight
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Profession:Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone do not result in adequate glycaemic control

However, it does not impact your weight quickly. It takes a considerable time of one to two years to get the results, as shown in some long-term studies. You should take up a healthy diet and lifestyle routine to support your weight loss efforts. Metformin boosts the calories that you burn during the workout. If you don’t exercise, you will not burn calories. The average weight loss after two years is about four to seven pounds.

Weight Loss Results

The weight loss results from metformin last as long as you take the medicine. Once you stop taking medication, there is a fair chance that you start gaining weight. Also, if you do not follow a healthy diet plan along with regular exercise, you may not be able to lose weight. There are fair chances that you return to your weight even during medication.

Metformin is not a magic diet pill that can reduce your weight drastically overnight. However, it does not cause weight gain. If you are not able to lose weight with it, you will not even gain it either. However, some medications for type 2 diabetes may lead to weight gain. If you are type 2 diabetic and obese, the doctor is likely to recommend metformin to lower your risk of diabetes and for metformin weight loss.

Off-label Metformin Use

As metformin is meant to cure diabetes, the doctor also prescribes metformin for non-diabetic patients who want to lose weight. It is not approved by the FDA to use metformin on non-diabetic patients to lose weight.

However, the effective results of this medication on weight loss encourage health practitioners to use this medication for weight loss as Off-label use for non-diabetic patients.

Weight Loss PCOS

PCOS (Poly-Cystic Ovary Syndrome) is one of the major reasons for Obesity or overweight in women nowadays. It is closely linked with insulin resistance. Even many physicians and gynecologists administered metformin for weight loss when the patient is diagnosed (metformin dosage) with PCOS.

PCOS affects the menstrual cycle and leads to infertility. Triggered by hormonal fluctuations, being overweight counts as a major cause of PCOS as well as diabetes.

Women who are trying to conceive can administer Metformin for the regulation of hormones and weight loss. When comes to Metformin and weight loss for PCOS, has a direct impact on losing weight. Rather, metformin for weight loss in non-diabetics helps to regulate the hormones and enhances insulin resistance.

What are the benefits of Metformin on non-diabetics?

Here are some of the considerable benefits of using Metformin for non-diabetics:

  • Manages the blood sugar
  • Regulates the insulin resistance
  • Curbs down hunger and promotes a healthy appetite
  • Aids in normal metabolism and fat metabolism of the body
  • Results with weight loss in some people
  • Supports hormonal functions at appropriate levels
  • Controls the oxidative stress
  • Promotes the blood flow

Weight Loss Dosage or Metformin dosage?

You must be cautious in taking any medicine in the prescribed dosage. It helps you prevent unnecessary side effects.

Metformin weight loss dosage varies with every individual. It is recommended to consult with the physician about taking metformin for weight loss in non-diabetics. The exact dosage requirement even for diabetics varies with every individual.

The brand, diet, lifestyle, extent of type 2 diabetes, and brand are the deciding factors on the appropriate dosage of metformin. Some of the common metformin weight loss dosage recommendations include the following.

For continuous and extended-release, you can choose from” metformin 500 mg weight loss” to 1000 mg tablets. No more than 2500 mg tablets are allowed in adults. In the case of liquid metformin, the dosage can range from 5 ml to 8 ml. The dosage shall not exceed 25 ml per day in adults.

How to Take Metformin to Lose Weight?

When it comes to weight loss, there are two rules for this medication

  • Eat healthily
  • stay active

Weight loss is the result of a calorie deficit. When you consume fewer calories than you burn, it leads to weight loss. Metformin for weight loss in non-diabetics should follow the below list of diet and lifestyle habits when they intend to lose weight:

  • Avoid carbonated and sugar-based drinks
  • Start and end your day with a glass of warm water
  • Drink a glass of water 20 minutes before a meal
  • Split your meals into several parts and eat throughout the day
  • Eat only when you are hungry, not you are bored
  • A strict no to processed foods
  • Develop the habit of portion control
  • Find a replacement for cravings for certain foods
  • Include whole and fresh foods in your diet as a major portion
  • Stay active
  • Exercise for 20 minutes a day
  • Do some mindful meditation for 10 to 15 minutes a day

What are the other causes of weight loss?

Metformin doesn’t need to always lead to weight loss. If you are experiencing quick weight loss with medication, there may be other possible reasons for this as follows:

  • Cancer
  • Depression
  • AIDS
  • Stress
  • Chronic obstructive pulmonary disease
  • Parkinson disease

These are certain health conditions that lead to a loss of appetite and ultimately lead to weight loss. There are a few thyroid medications that increase metabolism and help you to lose weight.

If you encounter some digestive issues like irritable bowel syndrome, diarrhea, etc.

What are the precautions to be taken while taking Metformin?

Metformin may cause mild to moderate side effects in a few people. The side effects generally include dizziness, lightheadedness, nausea, vomiting, etc.

There is a common query rather than fear, Can metformin cause hypoglycemia in non-diabetics? Hypoglycemia means low sugar levels in the body. Metformin just helps your body to use its insulin and maximize its efficacy to absorb the insulin.

The direct answer is No. Metformin even in diabetics does not directly reduce insulin or glucose levels. It helps with insulin resistance. So, it is not likely that metformin causes hypoglycemia in non-diabetics. However, you must not forget a major fact.

The type of food you eat, your eating or diet routine along how active you are eventually impact your glucose level in the body. In rare cases, metformin causes hypoglycemia in non-diabetics.

If you do not follow healthy habits, metformin does not result in weight loss. You can read the metformin weight loss success stories and seek information metformin weight loss forum about lifestyle and diet changes.

Losing weight is not about any specific medication or rapid diet.

You must go slow and steady to lose weight in healthy ways without any side effects. Also, there is a word of caution when you take metformin for weight loss. You should not get into fasting too often. The fasting state easily takes you into hypoglycemia when your body is used to metformin for a brief period.

There are no worries when your physician or gynecologist prescribes metformin for weight loss in non-diabetics for other reasons. In women, a doctor may prescribe metformin for weight loss PCOS condition and to regulate the menstrual cycle.

In men, a doctor may prescribe metformin to lose weight if he is diagnosed on the verge of getting diabetes.

When to consult a doctor?

If you are losing weight rapidly to facing an extreme loss of appetite or energy, you should consult your doctor. There may be other possible reasons for this weight loss which have been discussed above. Weight loss should always be gradual so that there would not be many side effects.

  • Here are some of the questions you may ask your doctor:
  • What should be a reasonable weight loss goal for you?
  • What should be the recommended exercise and diet plan which leads to healthy weight loss?
  • When should I stop medication?

Frequently Asked Questions

Can I take metformin to lose weight?

Although it is not recommended by the FDA, metformin can be used for weight loss in non-diabetic people safely. The studies have not shown any correlation between weight loss and metformin. The only theory that works is, that metformin leads to losing appetite which impacts your weight loss.

Should non-diabetics take Metformin?

Yes, non-diabetics can take metformin to reduce weight. Metformin is responsible for decreasing the glucose level absorbed by the body from food. It also possesses anti-cardiovascular and anti-cancer disease benefits. Hence, administered medication for Metformin increases the lifespan of non-diabetics.

What metformin is used for other than diabetes?

Some of the off-label uses for metformin are Weight loss, PCOS, prediabetes, and gestational diabetes. Metformin is generally used to treat diabetes type 2. It is often combined with other medications for the treatment.

Does Metformin reduce belly fat?

Metformin is effective in reducing overall body fat which includes abdominal fat reduction as well. Women suffering from PCOS jostle with abdominal fat which is impacted largely by the intake of a hypocaloric diet along with metformin.


When you check online, you can end up reading many metformin weight loss success stories. However, you must know about the dosage and how to take metformin to lose weight to retain efficacy.

Remember, metformin for weight loss in non-diabetics is not a miracle or magic pill for weight loss. Once you stop taking metformin to lose weight, you may regain the weight you have lost. So, it is mandatory to change your diet and make healthy lifestyle changes.

7 thoughts on “Metformin For Weight Loss in Non-Diabetics (2024)”

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